7/5/2023 0 Comments Antiplatelet medication![]() ![]() Even though each type works in a different way, all antiplatelet medicines help to keep platelets from sticking together and forming blood clots. There are many different types of antiplatelet medicines. Are there different types of antiplatelet medicines? Some patients with atrial fibrillation or valve disease also take antiplatelets. Stroke or transient ischemic attacks (TIAs)Īntiplatelets may also be given to patients during and after angioplasty and stent procedures and after coronary artery bypass surgery.Patients are usually given antiplatelets if they have a history of Antiplatelet medicines can stop blood clots from forming. Platelets can also cause blood clots to form around stents, artificial heart valves, and other devices that are placed inside the heart or blood vessels. When this happens, the platelets can cause a blood clot to form inside the vessel. But, sometimes, platelets will clump together inside a blood vessel that is injured, swollen (inflamed), or that has plaque build-up ( atherosclerosis). ![]() If you have a cut or a wound, this is a good thing. Whenever there is an injury in your body, platelets are sent to the site of the injury, where they clump together to form a blood clot. older age especially if frail, with serious co-morbidities, eg cardiovascular disease, hepatic or renal impairment, diabetes, hypertension.Antiplatelets are a group of medicines that stop blood cells (called platelets) from sticking together and forming a blood clot.concomitant use of medications known to increase the risk of GI bleeds (see BNF ).a history of gastroduodenal ulcer, GI bleeding or gastroduodenal perforation.** Patients at high risk of GI adverse effects are those with any of the following risk factors: immunocompromised or severe co-morbidity.co-prescription of high risk antibiotics namely clindamycin, cephalosporins, co-amoxiclav and fluoroquinolones (eg ciprofloxacin).a history of previous CDI or known colonisation with CDI (eg glutamate dehydrogenase (GDH) positive).*Patients at high risk of infection with CDI are those with any of the following risk factors : Consider the risk of CDI when prescribing antibiotics in the future. lansoprazole is indicated in dual therapy if age and co-morbidity confer a significant risk in the event of GI bleeding.Consider the risk of CDI when prescribing antibiotics in the future.Īntiplatelet dual therapy (low dose aspirin and clopidogrel/ticagrelor/prasugrel): patients with higher GI bleeding risk**: co-prescribe lansoprazole on initiation of antiplatelet monotherapy.patients with low gastrointestinal (GI) bleeding risk: if patients develop dyspepsia whilst on antiplatelet monotherapy consider co-prescription of ranitidine150mg twice daily initially if ineffective change to lansoprazole (start on treatment dose but aim to reduce to maintenance dose to minimise Clostridioides difficile ( CDI) risk*).Antiplatelet drugs (aspirin and clopidogrel) are not recommended for primary prevention of cardiovascular disease.Īntiplatelet monotherapy (low dose aspirin or clopidogrel):.See guidance on use post-MI, post-TIA or ischaemic stroke and Acute cornonary syndrome.For advice on initiating warfarin in patients taking antiplatelet agents, see Warfarin anticoagulant advice. ![]()
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